Aging & Stem Cell Exhaustion
Why regeneration declines with age: The stem cell exhaustion link.
The Body’s Constant Balancing Act
Every second, cells in your body are dying, while new ones are being created to replace them. This delicate equilibrium — the balance between repair and degeneration — is what keeps tissues healthy. But over time, our body’s ability to keep up with the damage falters.
“If our regeneration cannot keep up with the repair and dying of the cells, then the body declines over time.”— Dr. Yi Song
The Hallmarks of Aging
Compromised Autophagy
A breakdown in the body’s cellular recycling system that’s essential for clearing out damaged proteins and organelles.
Stem Cell Exhaustion
As we age, stem cells become depleted and less active, reducing the body's ability to repair and regenerate tissue.
A 250,000-Fold Decline in Regenerative Capacity
When we’re born, roughly 1 in every 10,000 cells is a stem cell. By the time we reach our 50s, that number drops to only 1 in 400,000. This cumulative loss in regenerative power doesn’t just mean slower healing—it sets the stage for a host of degenerative diseases.
Stem Cell Exhaustion and Aging
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